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Hek 293 cells were generated in 1973 by transfection of cultures of normal human embryonic kidney cells with sheared adenovirus 5 dna in alex van der eb 's laboratory in leiden, the netherlands. Human embryonic kidney 293 (hek293) cells are a human embryonic kidney cell line that has gained widespread popularity in the scientific community because of their versatility and usefulness in a wide range of research applications. Hek 293 is an acronym for “human embryonic kidney 293.” this cell line was developed in the early 1970s from human embryonic kidney cells
The origins of the name reveal a vital piece of context Its high transfectability, fast growth, and adaptability make it a top choice for both academic and industry labs. These cells were extracted from an aborted fetus, which has generated a significant amount of ethical debate in various circles.
Human embryonic kidney 293 (hek293) cells are a widely used cell line in biological research and biotechnology
They serve as a versatile platform for scientific investigations and the production of biological products. In this review, we discuss the use of hek293 cells and its subtypes in the production of biotherapeutics. Hek293 cell lines are defined as immortalized cell lines derived from human embryonic kidney cells that have been transformed with a fragment of adenovirus type 5 dna, leading to the development of various unique subtypes with distinct properties. The use of 293 refers to the experiment number referenced in his laboratory note book
There is still some debate as to cell type of origin. Hek 293 cell lines are commonly used in cancer research These organisms pose a moderate health hazard. The hek293 cell line is a permanent line established from primary embryonic human kidney, which was transformed with sheared human adenovirus type 5 dna
The adenoviral genes expressed in this cell line allow the cells to produce very high levels of recombinant proteins.
The hek293 cell line (human embryonic kidney 293) is one of the most widely used mammalian cell lines in life science research and biotechnology
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