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Increased number of patients with hemophilia have been identified to have osteoporosis at early ages This study attempts to assess the prevalence of low bmd (osteoporosis and osteopenia) and the associated risk factors in a group of iranian hemophilia patients. Low bone mineral density in the setting of hemophilia has been associated with decreased mobility, sedentary life style, on demand treatment or.
Several predisposing risk factors exist for decreased bone mineral density in patients with hemophilia increasing the likelihood of osteopenia and osteoporosis in this population Hemophilia c (fxi deficiency) has an autosomal recessive inheritance pattern, which means that both parents need to be carriers of the mutated gene to pass it on to their children. We report the findings of a study evaluating the association of vitamin d deficiency, osteoporosis and hemophilia.
Hemophilia c (also known as factor xi deficiency or rosenthal syndrome) is a rare form of hemophilia
Hemophilia is a blood disorder that happens when your blood doesn’t clot so your bleeding slows down or stops. In a study of young adults (median age 41.5 years), as many as 70% of patients with hemophilia exhibited decreased bmd, with 43% displaying osteopenia and 27% osteoporosis (). Now that people with hemophilia are living longer, it’s a crucial topic to address Studies have shown that blood clotting factor viii is essential to developing healthy bones.
A recent case series from australia suggested that children with hemophilia may be more likely to have low bone density or osteopenia than healthy controls. Patients with hemophilia (pwh) often have a high risk of osteoporosis and fractures that is usually ignored Herein, we review the underlying mechanisms of osteoporosis and the increased risk of fractures and their treatment in patients with fviii or fix deficiency.
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